Moonkyu Kim
Papers
1
Total Citations
19
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1
About
Moonkyu Kim is a molecular biologist whose pioneering work has centered on understanding gene expression dynamics in cellular differentiation and cancer biology. His most cited study, "Identification of Novel Genes Differentially Expressed in PMA-induced HL-60 Cells Using cDNA Microarrays" (2000), with 19 citations, established a foundational approach to uncovering genes involved in myeloid differentiation. By employing cDNA microarray technology on phorbol ester (PMA)-treated HL-60 leukemia cells, Kim identified previously unknown transcripts that are differentially regulated during the transition from proliferating to differentiated states. This work not only expanded the catalog of genes implicated in hematopoietic cell fate decisions but also provided early evidence for the power of genomic screening in leukemia research. Kim’s contributions have helped illuminate the molecular switches controlling differentiation, offering potential targets for therapeutic intervention in acute myeloid leukemia. His research continues to influence studies on gene regulation and cancer cell biology, demonstrating the lasting impact of his early, methodical exploration of the transcriptome.
Research Focus
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