Monia Trasolini

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About

Monia Trasolini is a clinical researcher whose work focuses on the intersection of dissociative disorders and treatment-resistant depression, with a particular emphasis on novel pharmacological interventions. Her most cited study, "REL-1017 (Esmethadone) May Rapidly Reduce Dissociative Symptoms in Adults With Major Depressive Disorder Unresponsive to Standard Antidepressants" (2022), represents a significant contribution to the field by exploring how esmethadone—a glutamatergic modulator—can address both depressive and dissociative symptoms in patients who have not responded to conventional treatments. This work is notable for highlighting the high prevalence of underdiagnosed dissociative disorders in psychiatric populations, noting that while 29% of outpatients experience dissociative symptoms, only 5% had previously received a diagnosis. With 6 citations, Trasolini’s research is gaining traction among clinicians and researchers seeking to bridge the gap between dissociative pathology and major depressive disorder. Her findings suggest that esmethadone may offer rapid relief for dissociative symptoms, opening new avenues for treating complex, comorbid psychiatric conditions. Trasolini’s work is particularly valuable for students and clinicians interested in the neurobiology of dissociation and the development of faster-acting antidepressants.