Mikkel Harndahl
Papers
1
Total Citations
91
H-Index
1
About
Mikkel Harndahl has made foundational contributions to the study of peptide binding to HLA class I molecules, a critical area in immunology and vaccine design. His work centers on developing and refining high-throughput, homogeneous assays to measure peptide-MHC interactions with unprecedented precision and scalability. His landmark 2009 paper, "Peptide Binding to HLA Class I Molecules: Homogenous, High-Throughput Screening, and Affinity Assays," has garnered 91 citations, establishing a gold-standard methodology that enables researchers to rapidly screen large peptide libraries for binding affinity. This technical breakthrough has accelerated the identification of immunogenic epitopes for infectious diseases and cancer, directly impacting T-cell-based immunotherapy development. Harndahl’s contributions extend beyond method development; his systematic characterization of HLA binding motifs has deepened our understanding of antigen presentation and immune recognition. By bridging biochemistry and immunoinformatics, his work remains essential for designing peptide-based vaccines and predicting immune responses. For students and researchers, Harndahl exemplifies how rigorous assay design can unlock new frontiers in translational immunology.
Research Focus
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Top Papers
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