Michael C. Bassik
Papers
1
Total Citations
102
H-Index
1
About
Michael C. Bassik is a pioneering geneticist and systems biologist whose research focuses on deciphering the functional architecture of the mammalian genome through high-throughput genetic screening. His major contributions lie in developing innovative pooled screening platforms that enable systematic mapping of genetic interactions, particularly in the context of cancer and cellular stress responses. His landmark 2014 paper, "Functional genomics platform for pooled screening and generation of mammalian genetic interaction maps," which has garnered over 102 citations, introduced a powerful method for identifying synthetic lethal relationships and drug targets. This work has had a profound impact on understanding how genes cooperate to maintain cellular fitness and resist therapeutic interventions. Bassik's research has been instrumental in advancing CRISPR-based functional genomics, providing tools that allow researchers to explore complex genetic networks with unprecedented precision. His achievements include pioneering approaches that bridge genetics and drug discovery, making him a leading figure in the field of functional genomics and a key contributor to the development of next-generation cancer therapies.
Research Focus
Key Achievements
Top Papers
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