Marlis Zeiler
Papers
1
Total Citations
31
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1
About
Marlis Zeiler is a leading figure in quantitative proteomics, with a primary focus on developing innovative methods for precise protein measurement. Her major contribution is the creation of the immuno-SILAC technique, a groundbreaking approach that combines immuno-based enrichment with stable isotope labeling and mass spectrometry. This method, detailed in her highly cited 2014 paper, enables the absolute quantification of target proteins within complex biological samples using polyclonal antibodies and affinity-purified recombinant standards. By integrating the specificity of antibodies with the accuracy of SILAC, Zeiler’s work addresses a critical need in proteomics: reliable, multiplexed quantification without the requirement for monoclonal antibodies. Her research has significant implications for biomarker discovery and clinical diagnostics, offering a robust tool for analyzing disease-related proteins. With 31 citations on this seminal paper, Zeiler’s contributions are recognized for bridging immunochemistry and mass spectrometry, providing a practical and scalable solution for quantitative proteomics. Her work continues to influence researchers seeking high-throughput, precise protein analysis in complex systems.
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