Mark C. Wenlock
Papers
1
Total Citations
38
H-Index
1
About
Mark C. Wenlock is a leading figure in pharmaceutical sciences, whose work centers on the critical physicochemical properties that govern drug discovery and development. His research focuses on advancing the understanding and measurement of key parameters like aqueous solubility, which is fundamental to a compound’s bioavailability and success as a therapeutic candidate. Wenlock’s major contribution lies in pioneering high-throughput methodologies that bridge the gap between rapid kinetic screening and rigorous thermodynamic equilibrium data. His highly cited 2011 paper, "A Highly Automated Assay for Determining the Aqueous Equilibrium Solubility of Drug Discovery Compounds" (38 citations), exemplifies this impact by introducing a robust, automated approach that provides more reliable solubility data early in the discovery pipeline. This work has helped shape modern drug design strategies, enabling researchers to make better-informed decisions on compound selection and optimization. Through his innovative assays and deep expertise in physicochemical profiling, Wenlock has significantly enhanced the efficiency of drug discovery, ensuring that promising candidates are not derailed by poor solubility later in development.
Research Focus
Key Achievements
Top Papers
- 1