Marco A. Mascarella
McGill University Health Centre, Jewish General Hospital, McGill University
Papers
6
Total Citations
33
H-Index
3
About
Marco A. Mascarella is an emerging clinician-researcher whose work sits at the intersection of head and neck oncology, surgical innovation, and patient-centered outcomes. His research has concentrated on human papillomavirus-associated oropharyngeal squamous cell carcinoma (HPV-OPSCC), a disease whose rising incidence has demanded new thinking about how best to treat patients while preserving their quality of life. Mascarella's most significant contributions center on neoadjuvant chemotherapy combined with transoral robotic surgery (TORS) as a de-escalation strategy for HPV-OPSCC. His work challenges the radiation-dominant treatment paradigm by demonstrating that surgery-first approaches can address distant metastasis — the leading cause of death in this population — while meaningfully reducing long-term toxicities. His quality-of-life studies have been particularly influential in translating clinical outcomes into patient-relevant measures, accumulating over 25 citations across a tightly focused body of work published primarily in high-impact otolaryngology journals. Beyond his clinical trials, Mascarella has contributed historical and conceptual perspective to the field, tracing how HPV's discovery catalyzed the adoption of robotic surgery. For students and researchers interested in surgical oncology and treatment de-escalation, his work represents a compelling reimagining of how HPV-related cancers should be managed.
Research Focus
Key Achievements
Top Papers
- 1
- 2
- 3
- 4
- 5
- 6