Marc Weiske
Papers
1
Total Citations
29
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1
About
Marc Weiske is a biotechnologist whose research focuses on microbial strain engineering and protein secretion, with a particular emphasis on *Corynebacterium glutamicum* as a platform organism. His major contribution lies in exploring genome reduction strategies to enhance heterologous protein production, as demonstrated in his most-cited work, “Screening of a genome‐reduced *Corynebacterium glutamicum* strain library for improved heterologous cutinase secretion” (2020, 29 citations). This study systematically investigated how deleting single or multiple gene clusters impacts the secretion of cutinase from *Fusarium solani pisi*, advancing the construction of streamlined microbial chassis for industrial biotechnology. By linking genome minimization to functional output, Weiske’s work provides valuable insights for optimizing secretion efficiency in *C. glutamicum*, a key organism in amino acid and enzyme production. His research sits at the intersection of synthetic biology and bioprocess engineering, offering practical tools for developing more efficient microbial factories. With growing interest in sustainable biomanufacturing, Weiske’s contributions are increasingly relevant for researchers aiming to harness genome-reduced strains for improved yields of recombinant proteins.
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