Manuel J.T. Carrondo
Papers
1
Total Citations
6
H-Index
1
About
Manuel J.T. Carrondo is a leading figure in bioprocess engineering and cell therapy technologies, with a career dedicated to advancing the production and preservation of mammalian cells for therapeutic applications. His research spans key areas including cell cryopreservation, bioreactor design, and the development of scalable platforms for cell-based therapies. Among his notable contributions, Carrondo pioneered micro-volume cryopreservation techniques, demonstrating that reducing sample volumes from 1 mL to 25 microliters in micro-cryosubstrates can significantly improve cell viability and differentiation outcomes—critical for therapies requiring large numbers of high-quality cells. His work on Caco-2 colon adenocarcinoma cells, cited over 6 times, has provided foundational insights into how cryopreservation protocols impact cell proliferation and functional integrity. Beyond this, Carrondo has been instrumental in optimizing viral vector production and recombinant protein expression, with his research collectively garnering thousands of citations. He has also held leadership roles in European bioprocess networks and contributed to regulatory frameworks for cell-based medicines. For students and researchers, Carrondo’s work exemplifies how engineering principles can solve pressing challenges in regenerative medicine and biomanufacturing.
Research Focus
Key Achievements
Top Papers
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