Madonna Grehan
Papers
1
Total Citations
176
H-Index
1
About
Madonna Grehan is a genetic epidemiologist whose research has significantly advanced the understanding of the genetic underpinnings of pre-eclampsia, a dangerous hypertensive disorder of pregnancy. Her most influential work, a 2000 genome scan involving families from Australia and New Zealand, confirmed the presence of a maternal susceptibility locus for pre-eclampsia on chromosome 2. This landmark study, which has garnered 176 citations, provided critical evidence for a genetic component to the condition, moving beyond environmental and immunological theories. By identifying this specific chromosomal region, Grehan’s research laid the groundwork for subsequent gene-mapping efforts and has been instrumental in guiding the search for causative variants. Her contributions have helped shape the field of reproductive genetics, offering hope for improved risk prediction and potential therapeutic targets for a condition that remains a leading cause of maternal and fetal morbidity worldwide.
Research Focus
Key Achievements
Top Papers
- 1