Louise Royle
Papers
1
Total Citations
78
H-Index
1
About
Louise Royle is a leading figure in glycobiology, whose work has fundamentally advanced the analysis of glycosylation in biopharmaceuticals. Her research centers on developing high-throughput, robust analytical methods to characterize the complex glycans attached to therapeutic proteins. Royle’s major contribution lies in pioneering automated permethylation techniques coupled with MALDI-TOF mass spectrometry, enabling the rapid, detailed, and reproducible profiling of N- and O-linked glycans. This work is critical for the biopharma industry, as glycosylation directly impacts a drug’s stability, efficacy, safety, and immunogenicity. Her most cited paper (78 citations) demonstrates the power of this approach for monitoring glycoprotein therapeutics throughout their lifecycle, supporting the adoption of Quality by Design (QbD) frameworks. By providing tools for consistent, high-fidelity glycan analysis, Royle has helped ensure the quality and safety of biologic drugs, making her a key contributor to the intersection of analytical chemistry and pharmaceutical development.
Research Focus
Key Achievements
Top Papers
- 1