Lotte C. Franken

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About

Dr. Lotte C. Franken is a leading surgical oncologist whose research focuses on advancing minimally invasive techniques for complex hepatopancreatobiliary (HPB) malignancies, particularly perihilar cholangiocarcinoma (PHC). Her seminal 2019 systematic review, cited 29 times, critically evaluated the feasibility and safety of minimally invasive surgery (MIS) for PHC—one of the most technically demanding procedures in HPB surgery. By synthesizing global outcomes, Dr. Franken demonstrated that while MIS offers potential advantages in recovery, its application in PHC requires careful patient selection and high-volume expertise. This work has guided clinical decision-making and shaped surgical training paradigms. Beyond this landmark review, Dr. Franken’s contributions include refining surgical approaches to improve oncologic outcomes and reduce morbidity in HPB cancers. Her research, recognized through citations and invited lectures, bridges the gap between innovation and safety in complex cancer surgery. For students and researchers, Dr. Franken’s work exemplifies how rigorous evidence can transform high-stakes surgical practice, inspiring further investigation into tailored MIS strategies for challenging tumors.