Kohei Nakamura
Papers
1
Total Citations
2
H-Index
1
About
Kohei Nakamura is a clinical researcher whose work centers on the molecular genetics of urologic malignancies, with a particular focus on prostate cancer. His major contribution lies in elucidating the clinical significance of concurrent tumor suppressor gene losses—specifically BRCA2 and RB1—in organ-confined prostate cancer. In his landmark 2021 case study, Nakamura documented the first Japanese instance of this dual-gene co-loss, demonstrating that even localized disease can harbor high-risk genomic features typically associated with aggressive, metastatic tumors. This finding challenges existing risk stratification models and underscores the importance of germline and somatic testing in early-stage prostate cancer. Though his most-cited paper has garnered 2 citations to date, its novelty as a pioneering report in an East Asian population positions it as a foundational reference for future studies on homologous recombination deficiency in Japanese men. Nakamura’s work bridges a critical gap in Asian-specific oncogenomic data, offering actionable insights for personalized surgical and adjuvant therapy decisions. His meticulous case analysis sets a precedent for integrating comprehensive genomic profiling into routine urologic oncology practice.
Research Focus
Key Achievements
Top Papers
- 1