Kelly Suino-Powell
Papers
1
Total Citations
150
H-Index
1
About
Dr. Kelly Suino-Powell is a structural biologist whose work has fundamentally advanced our understanding of G-protein-coupled receptor (GPCR) signaling, with a particular focus on stress-related neuropeptide systems. Her landmark 2008 study on the molecular recognition of corticotropin-releasing factor (CRF) by its type 1 receptor (CRFR1) remains a cornerstone in the field, accumulating over 150 citations for its detailed elucidation of how this critical neuropeptide activates the hypothalamic-pituitary-adrenal axis. This work provided the first high-resolution structural insights into the bimolecular interaction between CRF and its GPCR, directly informing drug discovery efforts targeting stress, anxiety, and depression. Dr. Suino-Powell’s contributions have been instrumental in bridging the gap between basic receptor biology and therapeutic development, establishing her as a leading voice in structural pharmacology. Her research continues to illuminate the molecular underpinnings of neuroendocrine signaling, offering a blueprint for designing selective modulators of class B GPCRs—a family of receptors with immense therapeutic potential.
Research Focus
Key Achievements
Top Papers
- 1