Kelly Monahan Agnew

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About

Kelly Monahan Agnew’s research centers on the intersection of aging, hormonal changes, and prostate cancer pathology, with a particular focus on how serum testosterone levels influence disease presentation. Her most-cited work, a 2017 study examining low serum testosterone in middle-aged men, revealed that preoperative testosterone deficiency correlates with more aggressive pathological features of prostate cancer. This finding is critical given that age is the primary risk factor for prostate cancer, and testosterone levels naturally decline with aging. By linking hormonal status to tumor characteristics, Agnew’s research provides a nuanced understanding of how endocrine changes may shape cancer progression, offering potential biomarkers for risk stratification. Her work has garnered 13 citations, reflecting its relevance to urologists and oncologists seeking to refine treatment approaches for older men. Agnew’s contributions underscore the importance of considering systemic hormonal environments in cancer biology, bridging endocrinology and oncology. Her findings encourage further investigation into whether testosterone replacement or modulation could alter prostate cancer outcomes, making her a thoughtful voice in the evolving dialogue on men’s health and aging.