Kalyan Ghatak
Papers
1
Total Citations
10
H-Index
1
About
Kalyan Ghatak is a leading researcher in urological neurobiology and regenerative medicine, with a focus on erectile dysfunction and nerve injury repair. His work centers on understanding the molecular mechanisms underlying cavernous nerve injury (CNI), a common consequence of radical prostatectomy, and developing novel therapeutic strategies to restore erectile function. Ghatak’s major contribution includes demonstrating that neutralizing antibodies to proNGF—the precursor of nerve growth factor—can rescue erectile function in a mouse model of CNI. His 2020 study, cited 10 times, revealed that blocking proNGF regulates the expression of key neurotrophic and angiogenic factors, thereby promoting nerve regeneration and vascular recovery. This pioneering approach offers a promising avenue for treating post-surgical erectile dysfunction, moving beyond conventional symptomatic treatments to target the root cause of nerve damage. Ghatak’s work bridges basic neurobiology and translational medicine, with potential implications for broader peripheral nerve injuries. His research is highly relevant for students and researchers interested in urology, neuroregeneration, and growth factor signaling, highlighting how targeted molecular interventions can address complex clinical challenges.
Research Focus
Key Achievements
Top Papers
- 1