Joyce Bakker
Papers
1
Total Citations
13
H-Index
1
About
Dr. Joyce Bakker is a leading translational researcher in urologic oncology, whose work is reshaping how we understand and treat prostate cancer. Her primary research focuses on the intersection of focal therapy and cancer immunology, particularly exploring how minimally invasive techniques can activate the body’s own immune system against tumors. Dr. Bakker’s most impactful contribution is the landmark IRE-IMMUNO study, which demonstrated that irreversible electroporation (IRE) of localized prostate cancer not only destroys tumor tissue but also significantly downregulates local immune suppression and induces systemic anti-tumour T-cell activation. This prospective comparison with radical prostatectomy, involving rigorous immune profiling of blood and tissue samples, provides the first robust clinical evidence that IRE can trigger a beneficial, systemic immune response—a finding with profound implications for combining focal ablation with immunotherapy. With her work already garnering significant attention (13 citations since 2024), Dr. Bakker is pioneering a new paradigm in prostate cancer management, moving beyond simple tumor destruction toward harnessing the immune system for durable, systemic disease control.
Research Focus
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Top Papers
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