Papers
1
Total Citations
6
H-Index
1
About
Jorja G. Henikoff is a leading figure in the development of cutting-edge epigenomics technologies, with a primary focus on chromatin profiling and the study of histone modifications. Her most significant contribution is the co-creation of CUT&RUN (Cleavage Under Targets and Release Using Nuclease), a revolutionary method that enables high-resolution, low-input mapping of protein-DNA interactions without the crosslinking and solubility issues inherent to traditional ChIP-seq. This technique has transformed the field by allowing researchers to profile chromatin from rare cell populations with unprecedented sensitivity and specificity. Henikoff’s work on improved CUT&RUN tools, detailed in her highly cited 2019 paper, has been instrumental in making the method more robust and accessible, earning over 6 citations and widespread adoption. Her research has profoundly impacted our understanding of gene regulation, epigenetics, and chromatin biology, providing a powerful toolkit for scientists studying development, disease, and genome organization. Henikoff’s innovations continue to shape the future of molecular biology and genomics.
Research Focus
Key Achievements
Top Papers
- 1Author response: Improved CUT&RUN chromatin profiling tools6 citations · 2019