Jillian Acevedo‐Skrip
Papers
1
Total Citations
6
H-Index
1
About
Dr. Jillian Acevedo-Skrip is a pioneering biotechnologist whose work sits at the critical intersection of analytical method development and mRNA vaccine safety. Her primary research focus is the characterization and quantitation of process-related impurities in nucleic acid therapeutics, a field essential to ensuring the potency and safety of next-generation vaccines. Her most impactful contribution to date is the development and application of an automated sandwich ELISA for the precise quantitation of residual double-stranded RNA (dsRNA) in mRNA vaccines. This work, published in 2024 and already garnering 6 citations, directly addresses a major manufacturing challenge: dsRNA is a common byproduct of the in vitro transcription reaction that can trigger unwanted immune responses and compromise vaccine efficacy. By creating a robust, high-throughput assay, Dr. Acevedo-Skrip has provided the industry with a critical tool for quality control, enabling more reliable and safer mRNA-based products. Her achievement is particularly notable for its immediate translational relevance, bridging the gap between fundamental analytical chemistry and real-world pharmaceutical production. As the mRNA platform continues to expand, her contributions to impurity profiling will remain foundational for both regulatory compliance and patient safety.
Research Focus
Key Achievements
Top Papers
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