Jeff E. Mandel

About

Jeff E. Mandel is a leading anesthesiologist and researcher whose work centers on the intersection of anesthesia, airway management, and sleep-disordered breathing. His primary contributions lie in refining drug-induced sleep endoscopy (DISE) for obstructive sleep apnea (OSA) patients. Mandel pioneered quantitative airway analysis during DISE, demonstrating that collapse occurs at multiple upper airway levels—a finding that reshaped diagnostic and surgical planning. His 2012 paper on this topic (56 citations) remains a foundational reference. He further advanced clinical safety by developing a probability ramp propofol infusion system, enabling reliable sedation for severe OSA patients without compromising airway patency (2014, 42 citations). Mandel also addressed anesthetic challenges in transoral robotic surgery, a critical area for head and neck cancer and OSA interventions. His 2017 review on DISE serves as a practical guide for anesthesia providers establishing new programs. With over 140 total citations, Mandel’s work has directly influenced perioperative protocols and sleep surgery outcomes, bridging anesthesiology and otolaryngology to improve patient safety and procedural efficacy.

Research Focus

Key Achievements

Top Papers

1. 1
   Quantitative airway analysis during drug‐induced sleep endoscopy for evaluation of sleep apnea

   56 citations · 2012
2. 2
   Safety and Efficacy of Drug-Induced Sleep Endoscopy Using a Probability Ramp Propofol Infusion System in Patients with Severe Obstructive Sleep Apnea

   42 citations · 2014
3. 3
   Anesthetic Considerations for Transoral Robotic Surgery

   32 citations · 2010
4. 4
   Drug-induced sleep endoscopy

   16 citations · 2017
5. 5
   Preface

   2 citations · 2010

Key Collaborators

Contact & Links