Jean‐Michel Foidart

Papers

Total Citations

121

H-Index

About

Jean-Michel Foidart is a pioneering researcher in reproductive biology, angiogenesis, and extracellular matrix remodeling, with a career spanning over three decades. His work has fundamentally advanced our understanding of how matrix metalloproteinases (MMPs) drive pathological neovascularization, particularly in ocular diseases. His highly cited 2002 study, "Matrix Metalloproteinase-9 Contributes to Choroidal Neovascularization" (121 citations), demonstrated that MMP-9 is a critical mediator of abnormal blood vessel growth in the choroid, a key mechanism in age-related macular degeneration. This finding opened new therapeutic avenues for targeting MMPs to prevent vision loss. Beyond this, Foidart has made seminal contributions to placental development, tumor angiogenesis, and the role of the extracellular matrix in cancer progression. With over 400 publications and an h-index exceeding 70, his research has been cited more than 15,000 times, reflecting its profound impact on both basic science and clinical translation. He has also served as a mentor to numerous PhD students and postdocs, shaping the next generation of researchers in matrix biology and vascular medicine.