Jane M. Carlton

Papers

Total Citations

H-Index

About

Jane M. Carlton is a leading figure in genomic and evolutionary biology, with a primary focus on the parasites that cause malaria and other tropical diseases. Her research integrates comparative genomics, population genetics, and molecular evolution to unravel the complex biology of pathogens like *Plasmodium* and *Leishmania*. A landmark contribution is her work on the genome sequencing and comparative genomics of tropical disease pathogens, exemplified by her 2003 study that helped pioneer the application of high-throughput technologies to eukaryotic parasites—work that has garnered over 1,600 citations and laid critical groundwork for understanding parasite evolution and drug resistance. Carlton has also made significant strides in characterizing the genetic diversity of *Plasmodium vivax*, the most widespread human malaria parasite, and has led major initiatives to sequence and analyze the genomes of multiple *Plasmodium* species. Her achievements include leadership roles in international genome consortia and recognition as a fellow of the American Association for the Advancement of Science. Through her research, Carlton has fundamentally advanced our understanding of how genomic variation drives pathogen biology, offering new avenues for vaccine and drug development.