Jan Hendrickx

Diagenode (Belgium), Amsterdam University Medical Centers

Papers

Total Citations

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About

Jan Hendrickx is a clinical researcher whose work bridges two seemingly distinct domains: epigenomics and head and neck oncology. Early in their career, Hendrickx contributed to the automation of ChIP-seq protocols, enabling epigenetic profiling from as few as 10,000 HeLa cells—a technical advance that made high-throughput chromatin analysis more accessible (6 citations). More recently, Hendrickx has focused on carcinoma of unknown primary (CUP) in head and neck cancer, particularly HPV-related oropharyngeal squamous cell carcinoma. Their 2023 study on diagnostics and the potential of transoral surgery (4 citations) helped clarify the role of transoral robotic surgery (TORS) in identifying occult primary tumors. Building on this, their 2024 work on swallowing outcomes after TORS and adjuvant treatment (3 citations) provided critical functional data for patients undergoing this combined approach. By integrating surgical innovation with patient-reported outcomes, Hendrickx has advanced both the technical and clinical dimensions of CUP management, offering new insights into diagnosis, treatment, and quality of life.