James Dennis
Papers
1
Total Citations
23
H-Index
1
About
James Dennis is a pioneering biochemist whose research has centered on glycobiology, specifically the roles of glycosyltransferases in cellular communication and disease. His most notable contribution is the development of a solid-phase glycosyltransferase assay, detailed in his 1999 paper, which enabled high-throughput screening for drug discovery. This innovation, cited 23 times, provided a critical tool for identifying inhibitors of glycosylation pathways, opening new avenues for therapeutic intervention in cancer and inflammatory diseases. Dennis’s work has illuminated how glycan structures on cell surfaces influence immune recognition and tumor progression, bridging fundamental biochemistry with translational medicine. His assay remains a foundational method in glycobiology labs, underscoring his impact on both basic research and pharmaceutical development. Through this and related studies, Dennis has advanced our understanding of the “glycocode,” positioning him as a key figure in the field.
Research Focus
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Top Papers
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