Hoke Han

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About

Hoke Han is a leading figure in stereotactic body radiation therapy (SBRT), with a particular focus on its application to early-stage lung cancer. His landmark 2007 study on CyberKnife® radiosurgery for Stage I lung cancer, which has garnered 86 citations, provided pivotal evidence for the efficacy and safety of this non-invasive treatment. Han’s work demonstrated that high-dose, precisely targeted radiation could achieve excellent local control rates with minimal toxicity, fundamentally shifting the treatment paradigm for patients who are not surgical candidates. Beyond this seminal contribution, his research has advanced the understanding of dose fractionation, tumor motion management, and long-term outcomes in SBRT. Han’s findings have been instrumental in establishing SBRT as a standard-of-care option, influencing clinical guidelines worldwide. His meticulous follow-up data at 36 months offered some of the earliest robust evidence of durable tumor control, cementing his reputation as a pioneer in the field. For students and researchers, Han’s work exemplifies how rigorous clinical investigation can translate into life-changing therapies for cancer patients.