Ho Bin Seo
Papers
1
Total Citations
24
H-Index
1
About
Dr. Ho Bin Seo is a pioneering researcher in the field of high-throughput biosensor technology and pharmaceutical screening. His most cited work, "High-throughput prescreening of pharmaceuticals using a genome-wide bacterial bioreporter array" (2015, 24 citations), introduced a groundbreaking approach to drug safety assessment. By engineering a panel of 15 luminescent recombinant *Escherichia coli* bioreporters, Dr. Seo demonstrated how bacterial stress responses can be harnessed to rapidly prescreen large pharmaceutical libraries—in this case, 420 compounds—for potential toxicity or biological activity. This innovative method offers a cost-effective, scalable alternative to traditional animal testing, enabling early-stage identification of hazardous compounds. Dr. Seo’s contributions have significant implications for reducing drug development costs and improving pharmaceutical safety. His work bridges synthetic biology and environmental toxicology, providing a powerful tool for both academic researchers and industry scientists. With a focus on developing rapid, genome-wide prescreening platforms, Dr. Seo continues to advance the field of bioreporter-based bioassays, making him a notable figure in the intersection of biotechnology and drug discovery.
Research Focus
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Top Papers
- 1