Harun Budak
Papers
1
Total Citations
3
H-Index
1
About
Harun Budak is a developmental biologist whose research focuses on the molecular mechanisms governing embryogenesis, with a particular emphasis on cholesterol metabolism and its critical role in vertebrate development. His most cited work, "A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo" (2015), provides a foundational atlas detailing how cholesterol and its biosynthetic intermediates are spatially and temporally regulated during development. This study illuminates cholesterol's multifaceted roles—from membrane biogenesis and steroidogenesis to the posttranslational modification of Hedgehog (Hh) signaling proteins, a pathway essential for patterning and growth. By mapping enzyme expression across embryonic tissues, Budak's research offers key insights into how disruptions in cholesterol biosynthesis can lead to congenital malformations. Though his citation count is modest, his contributions are significant for researchers studying developmental signaling, lipid biology, and the etiology of sterol-related birth defects. Budak’s work serves as a valuable resource for connecting metabolic pathways to complex developmental processes, highlighting the indispensable role of cholesterol in shaping the vertebrate embryo.
Research Focus
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Top Papers
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