Graeme MacLennan
Papers
2
Total Citations
302
H-Index
2
About
Graeme MacLennan is a leading biostatistician and trial methodologist whose work sits at the intersection of evidence synthesis, perioperative care, and patient-reported outcomes. He is best known for his contributions to surgical oncology, particularly in renal cancer, where his landmark 2012 systematic review of perioperative and quality-of-life outcomes following surgical management of localised renal cancer has amassed 288 citations, shaping clinical decision-making in urological oncology. MacLennan’s methodological expertise is further demonstrated through his leadership of high-impact randomised controlled trials, including the ALLEGRO trial—a placebo-controlled investigation of intravenous lidocaine to accelerate gastrointestinal recovery after colorectal surgery. This trial addresses a critical clinical problem: up to 40% of patients experience delayed GI function postoperatively, and MacLennan’s work provides rigorous evidence to guide perioperative care. His research consistently bridges rigorous statistical design with meaningful patient-centred outcomes, making him a pivotal figure in evidence-based surgery. Through his contributions to trial design, systematic review methodology, and surgical recovery research, MacLennan has advanced both the science and practice of perioperative medicine, influencing how surgeons and anaesthetists optimise recovery pathways for thousands of patients.
Research Focus
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Top Papers
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