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41
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About
Ghislaine Merle is a researcher whose work sits at the critical intersection of virology, food safety, and molecular diagnostics. Her primary research focuses on the detection and quantification of foodborne viruses—particularly hepatitis A virus and norovirus—in complex environmental and food matrices. Merle’s major contribution lies in the optimization and validation of automated nucleic acid extraction protocols for viral RNA from challenging samples like bottled water, shellfish, and soft fruits. Her most cited work, a 2009 study on the use of the robotic NucliSens® easyMAG™ platform for real-time RT-PCR detection of hepatitis A virus in bottled water, has garnered 41 citations. This paper demonstrated that automated purification could match or exceed manual methods in sensitivity and reproducibility, while drastically reducing hands-on time and contamination risk. The impact of this work is evident in its adoption by food safety laboratories seeking standardized, high-throughput screening methods. Merle’s research has directly contributed to improving the reliability of viral surveillance in the food supply chain, making her a key figure in applied virology and public health protection.
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