Gary R. Manchee
Papers
1
Total Citations
3
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1
About
Gary R. Manchee is a bioanalytical chemist whose work has advanced the field of pharmaceutical analysis, particularly in the development of automated methods for drug quantification in biological matrices. His research focuses on high-performance liquid chromatography (HPLC) and solid-phase extraction (SPE) techniques, with a key contribution being the creation of a fully automated assay for determining GR117289X in human plasma. This method, detailed in his 1994 paper, combined mixed-mode SPE with HPLC and ultraviolet detection, streamlining the process for reliable, high-throughput drug monitoring—a critical need in clinical pharmacokinetics. While his most cited work has garnered 3 citations, its significance lies in its pioneering approach to automation, reducing manual error and improving efficiency in bioanalysis. Manchee’s efforts underscore the importance of method development in supporting drug development and therapeutic monitoring, making his contributions a foundational reference for researchers seeking to optimize analytical workflows. His work exemplifies the meticulous science behind ensuring drug safety and efficacy.
Research Focus
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Top Papers
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