Florencia Pauli
Papers
1
Total Citations
36
H-Index
1
About
Florencia Pauli is a leading figure in functional genomics, with a primary focus on developing and applying high-throughput methods for mapping protein-DNA interactions. Her most cited work, "Fully automated high-throughput chromatin immunoprecipitation for ChIP-seq: Identifying ChIP-quality p300 monoclonal antibodies" (2014, 36 citations), exemplifies her major contribution: pioneering automated, scalable ChIP-seq protocols. This work not only streamlined the identification of high-quality antibodies for the critical cofactor p300 but also established a robust, reproducible framework for genome-wide mapping of transcription factor occupancy, cofactor binding, and histone modifications. By moving ChIP-seq from a manual, low-throughput technique to an automated, high-throughput platform, Pauli has enabled large-scale consortium projects and accelerated discoveries in gene regulation. Her impact is felt across the field, as her methodologies have become foundational for studies requiring systematic, unbiased mapping of the regulatory landscape. Pauli’s achievements lie in bridging engineering and biology, creating tools that empower researchers to explore the dynamic interplay between proteins and DNA with unprecedented efficiency and reliability.
Research Focus
Key Achievements
Top Papers
- 1