Fengchan Han

Papers

Total Citations

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About

Fengchan Han is a researcher whose work bridges molecular diagnostics and infectious disease, with a particular focus on *Helicobacter pylori*—a pathogen linked to gastric ulcers and cancer. Han’s key research areas include protein array technology, serological profiling, and host-pathogen interactions. Their most cited paper, “Detection of *H. pylori* antibody profile in serum by protein array” (2006, 9 citations), represents a significant methodological contribution. In this study, Han developed a protein array to simultaneously detect multiple *H. pylori* antibodies—specifically targeting urease B subunit (UreB), vacuolating toxin A (VacA), and cytotoxin-associated gene A protein (CagA)—in human serum. This approach enabled a more comprehensive and efficient serological diagnosis compared to traditional single-antibody tests, offering potential for improved screening and epidemiological studies. While Han’s citation impact is modest, their work exemplifies the early application of multiplex protein arrays to infectious disease serology, laying groundwork for later advances in high-throughput diagnostics. Han’s contributions are notable for their technical innovation in antigen preparation and array design, which could inform future studies on *H. pylori* pathogenesis and vaccine development.