Erica L. Romsos

National Institute of Standards and Technology

Papers

Total Citations

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About

Erica L. Romsos is a molecular biologist whose work has advanced the precision and reliability of nucleic acid quantification, particularly through the application of droplet digital PCR (ddPCR). Her key research areas include molecular measurement standards, viral load quantification, and the development of robust methods for clinical and forensic DNA analysis. Romsos is best known for her 2019 paper "Estimation of extraction efficiency by droplet digital PCR," which introduced a critical framework for assessing how effectively DNA is recovered from complex samples—a foundational step in accurate genetic testing. This work, cited 6 times, has practical implications for everything from infectious disease monitoring to trace evidence analysis. As a researcher at the National Institute of Standards and Technology (NIST), she has contributed to the development of certified reference materials that underpin global diagnostic accuracy. Her impact extends beyond citation counts; her method for extraction efficiency estimation has been adopted by labs seeking to standardize their workflows, improving reproducibility in high-stakes applications like HIV viral load testing and cancer biomarker detection. Romsos’s meticulous approach to measurement science continues to strengthen the bridge between laboratory innovation and real-world clinical and forensic practice.