Derrick Brittain
Papers
1
Total Citations
12
H-Index
1
About
Derrick Brittain is a neuroscientist and engineer whose work sits at the critical intersection of automation and connectomics. His primary research focuses on developing scalable methods for high-resolution brain mapping, specifically through serial section transmission electron microscopy (ssTEM). Brittain’s most notable contribution is the creation of LASSO: Loop-based Automated Serial Sectioning Operation, a groundbreaking technique designed to overcome the bottlenecks of manual tissue processing. By automating the collection of thousands of ultrathin sections, LASSO dramatically increases throughput while reducing costs, making large-scale neuroanatomical studies more feasible. Though his seminal 2018 paper has accumulated 12 citations, its influence is growing as the field pivots toward whole-brain reconstructions. Brittain’s work is particularly significant for its potential to democratize connectomics—enabling labs with limited resources to participate in mapping complex neural circuits. His achievements represent a pivotal step toward realizing the long-sought goal of a complete structural wiring diagram of the mammalian brain.
Research Focus
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Top Papers
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