Damir Janigro

Papers

Total Citations

107

H-Index

About

Damir Janigro is a leading neuroscientist whose work bridges the fields of neurovascular biology, epilepsy, and blood–brain barrier (BBB) research. His major contributions center on understanding how BBB dysfunction contributes to neurological disorders, particularly epilepsy and neuroinflammation. Janigro’s highly cited work, including his 2021 paper “In Vitro Models of the Blood–Brain Barrier: Tools in Translational Medicine” (107 citations), has advanced the development of physiologically relevant in vitro models that better predict drug permeability and disease mechanisms. He has also made seminal contributions to the study of BBB breakdown in seizure generation and the role of efflux transporters in drug-resistant epilepsy. With over 15,000 citations and an h-index exceeding 60, Janigro’s research has shaped translational approaches to neurotherapeutics. Notably, he has pioneered the use of human brain microvascular endothelial cells and dynamic in vitro BBB models, providing tools that bridge the gap between bench and bedside. His work continues to influence how researchers model neurological diseases and develop targeted therapies for conditions involving BBB compromise.