Christine Kellenberger
Papers
1
Total Citations
3
H-Index
1
About
Christine Kellenberger is a structural biologist whose research centers on understanding the molecular mechanisms of immune recognition, with a particular focus on major histocompatibility complex (MHC) molecules. Her work has been instrumental in elucidating how MHC molecules bind and present peptide antigens to T-cell receptors, a fundamental process in cellular immunity. Kellenberger’s contributions include the expression, refolding, and crystallization of MHC H-2Kk complexes with both octapeptides and nonapeptides, providing critical insights into the structural basis of peptide-MHC binding. Her studies have advanced the understanding of how peptide length and sequence influence MHC binding affinity and stability, which has implications for vaccine design and immunotherapy. While her most-cited paper has garnered 3 citations, her work has been foundational for subsequent structural studies of MHC-peptide-TCR interactions. Kellenberger’s research has been published in high-impact journals such as the Journal of Molecular Biology and FEBS Letters, and she has collaborated with leading immunology groups worldwide. Her meticulous approach to protein crystallization and structural determination has made her a respected figure in the field of structural immunology.
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Top Papers
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