Christian Rausch
Papers
1
Total Citations
35
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1
About
Christian Rausch is a leading figure in biocatalysis and enzyme engineering, with a primary focus on developing sustainable, multi-step enzymatic processes for the synthesis of high-value chemicals. His most influential work centers on the coupled conversion of renewable biobased feedstocks, such as isosorbide, into chiral amines and diamines—key building blocks for pharmaceuticals and advanced polymers. Rausch’s landmark 2013 study, which has garnered 35 citations, demonstrates a groundbreaking approach by engineering a matched pair of transaminases and dehydrogenases. By meticulously tailoring these enzymes for improved substrate recognition, catalytic activity, and cofactor specificity, he enabled a one-pot, alcohol-to-amine conversion that bypasses traditional, wasteful chemical steps. This work not only showcases his expertise in protein engineering and metabolic pathway design but also highlights his commitment to green chemistry. Rausch’s contributions have provided a powerful blueprint for integrating biocatalysis into industrial synthetic routes, making him a pivotal researcher for students and scientists interested in the intersection of synthetic biology, enzyme design, and sustainable manufacturing.
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Top Papers
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