Charles Moore-Kelly
Papers
1
Total Citations
23
H-Index
1
About
Charles Moore-Kelly is a leading researcher in biophysical characterization and protein analytics, with a primary focus on advancing methods for assessing the physical stability of biotherapeutics. His most cited work, published in 2019, introduces an innovative automated high-throughput platform that integrates capillary circular dichroism with intrinsic fluorescence spectroscopy. This breakthrough enables rapid, simultaneous determination of protein secondary and tertiary structure, addressing a critical bottleneck in the development, manufacture, and formulation of therapeutic proteins. By robotically injecting samples into a capillary flow cell, the system dramatically increases throughput while reducing sample volume requirements, making it a powerful tool for early-stage drug discovery and quality control. With 23 citations, this paper has already influenced the field by demonstrating how automation can enhance the efficiency and reproducibility of biophysical assays. Moore-Kelly’s contributions are particularly valuable for researchers working on protein stability, formulation science, and bioprocess development, offering a practical solution to a longstanding challenge in the biopharmaceutical industry.
Research Focus
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Top Papers
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