Papers
5
Total Citations
152
H-Index
5
About
Dr. C. Keller is a leading clinical researcher in stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT), with a focus on precision radiation oncology for brain metastases, lung tumors, and prostate cancer. Their major contributions include demonstrating the feasibility and efficacy of repeated in-field radiosurgery for locally recurrent brain metastases—a heavily treated patient cohort where re-irradiation was previously considered high-risk—with a landmark 2018 study accumulating 61 citations. Dr. Keller has also advanced motion-compensated SBRT techniques, notably through robotic-guided systems that optimize mean gross tumor volume (GTV) dose for lung tumors, achieving high local control with minimal toxicity in a 208-patient study (30 citations). Their work on breathing-motion-compensated robotic SBRT (29 citations) has improved treatment accuracy for moving targets. Additionally, Dr. Keller has explored hypo-fractionated SBRT for localized prostate cancer, demonstrating feasibility in a bi-center German trial (16 citations), and provided real-world dosimetric comparisons between CyberKnife SBRT and HDR brachytherapy (16 citations). These contributions have shaped modern practice in stereotactic radiation, offering effective, non-invasive options for complex and recurrent cancers.
Research Focus
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Top Papers
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