Bruno Lorenzi

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About

Bruno Lorenzi is a surgical innovator whose work centers on advancing minimally invasive techniques for esophageal cancer treatment, with a particular focus on improving the safety and efficacy of esophagectomy procedures. His major contributions lie in refining the totally minimally invasive two-stage esophagectomy, notably through the development and validation of the intrathoracic hand-sewn esophagogastric anastomosis performed in the prone position. This technique, detailed in his most-cited paper (11 citations), represents the largest study of its kind, challenging the conventional reliance on mechanical or robotic anastomosis and offering a reproducible alternative that may reduce complications. Lorenzi’s research also addresses rare but critical postoperative complications, as demonstrated by his case report on the transmural migration of a Hem-o-lok clip from the azygous vein (4 citations)—the first documented instance of this phenomenon following minimally invasive esophagectomy. By documenting such novel adverse events, he provides essential insights for surgical vigilance and patient management. His work has a direct impact on clinical practice, offering surgeons evidence-based refinements that enhance patient outcomes. Lorenzi’s contributions are particularly valuable for trainees and researchers in thoracic and upper gastrointestinal surgery, as they bridge the gap between technical innovation and real-world surgical challenges.