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About

Brice Passera is a leading researcher in non-invasive brain stimulation, whose work has fundamentally advanced our understanding of cortical organization and excitability. His primary research areas focus on transcranial magnetic stimulation (TMS) methodologies, particularly in developing multi-scale mapping techniques that integrate TMS with electroencephalography (EEG) and electromyography (EMG). Passera’s major contributions include pioneering the use of TMS-EEG coupling to probe regional cortical excitability through input-output properties, a framework that has garnered 44 citations and reshaped how researchers assess modular cortical dynamics. He also developed an automatized set-up procedure for TMS protocols (31 citations), significantly improving experimental reproducibility and accessibility. In a landmark proof-of-principle study, Passera demonstrated the first combined multi-dimensional TMS mapping in patients with Parkinson’s disease undergoing deep brain stimulation, revealing cross-scale and cross-dimensional organizational features of the motor cortex. This work, though recent with 6 citations, represents a critical step toward personalized neuromodulation therapies. Passera’s innovative integration of cutting-edge TMS-EMG and TMS-EEG approaches continues to drive translational neuroscience, offering new windows into cortical function and dysfunction.