Andrew Teasdale
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36
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About
Andrew Teasdale is a leading figure in pharmaceutical analytical chemistry, renowned for his pioneering work in genotoxic impurity control and safety assessment. His research focuses on the development of robust analytical methods to detect and quantify trace-level impurities that pose significant risks to patient health. A major contribution is his landmark 2008 study, which introduced an automated static headspace gas chromatography–mass spectrometry (SHS-GC–MS) method for monitoring the formation of ethyl methane sulfonate—a potent genotoxic impurity—from ethanol and methane sulfonic acid. This work, cited 36 times, provided a critical framework for understanding and mitigating the risks of sulfonate esters in drug substances. Teasdale’s broader impact includes co-authoring key industry guidelines and regulatory white papers that shape global impurity control strategies. His methodical approach to solving complex analytical challenges has made him an indispensable resource for pharmaceutical scientists, ensuring safer medicines through rigorous impurity profiling.
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