Andrew M. Jenner
Papers
1
Total Citations
86
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1
About
Andrew M. Jenner is a leading figure in lipidomics, with a primary research focus on the development and application of advanced analytical methods for studying lipid biology in human health and disease. His most significant contribution is the creation of a groundbreaking, high-throughput lipid extraction protocol for human brain tissue, detailed in his 2013 paper, which has garnered 86 citations. This work directly addressed a critical bottleneck in the field by replacing the laborious, traditional Folch method with a more efficient methyl-tert-butyl ether (MTBE) extraction combined with mechanical homogenization. By enabling the rapid, reproducible, and comprehensive analysis of complex brain lipid profiles, Jenner’s methodology has become a cornerstone for researchers investigating neurological disorders, from Alzheimer’s to multiple sclerosis. His innovation not only accelerated the pace of discovery but also improved data quality, making large-scale lipidomic studies feasible. Through this pivotal achievement, Jenner has profoundly impacted our understanding of the brain’s molecular landscape, establishing himself as a key innovator in the quest to link lipid dysregulation to disease pathology.
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