Alf A. Lindberg

About

Alf A. Lindberg has made foundational contributions to the rapid detection and serotyping of bacterial pathogens, with a particular focus on *Salmonella* and diarrheal diseases. His research centers on molecular diagnostics, microbial pathogenesis, and the immunochemistry of bacterial surface antigens. Among his most cited works is a 1997 study introducing a digoxigenin-based enzyme-linked immunosorbent assay (DIG-ELISA) to detect PCR products of the *rfbS* gene from serogroup D salmonellae. This rapid screening prototype, which has garnered 57 citations, demonstrated high sensitivity for identifying *Salmonella* in stool specimens—a critical advance for clinical and epidemiological surveillance. Lindberg’s broader body of work, including his influential studies on *Vibrio cholerae* and *Shigella* lipopolysaccharides, has shaped our understanding of bacterial O-antigen structure and its role in virulence. His innovative integration of PCR with ELISA techniques helped bridge molecular biology and practical diagnostics, enabling faster, more accurate pathogen detection. With hundreds of citations across his career, Lindberg’s research remains a cornerstone for scientists working on enteric infections, vaccine development, and molecular epidemiology.

Research Focus

Key Achievements

Top Papers

1. 1
   An enzyme-linked immunosorbent assay to detect PCR products of the rfbS gene from serogroup D salmonellae: a rapid screening prototype

   57 citations · 1997

Key Collaborators

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