Bristol-Myers Squibb (Germany)

An Automated Liquid Chromatography-Mass Spectrometry Process to Determine Metabolic Stability Half-Life and Intrinsic Clearance of Drug Candidates by Substrate Depletion

134 次引用 · 2008

📊 篇均引用: 29

📈 最高产年份: 2008 (1)

🔬 研究焦点: Chemistry, Chromatography, Mass spectrometry, Liquid chromatography–mass spectrometry, Analytical Chemistry (journal), Biochemistry

代表论文

1
An Automated Liquid Chromatography-Mass Spectrometry Process to Determine Metabolic Stability Half-Life and Intrinsic Clearance of Drug Candidates by Substrate Depletion
134 次引用 · 2008
2
Comparison of plasma sample purification by manual liquid–liquid extraction, automated 96-well liquid–liquid extraction and automated 96-well solid-phase extraction for analysis by high-performance liquid chromatography with tandem mass spectrometry
79 次引用 · 1999
3
Internal standard tracked dilution to overcome challenges in dried blood spots and robotic sample preparation for liquid chromatography/tandem mass spectrometry assays
38 次引用 · 2011
4
Process analytics 4.0: A paradigm shift in rapid analytics for biologics development
16 次引用 · 2021
5
Adjunct Automation to the Cellmate™ Cell Culture Robot
14 次引用 · 2004
6
Cell-based assay of MGAT2-driven diacylglycerol synthesis for profiling inhibitors: use of a stable isotope-labeled substrate and high-resolution LC/MS
11 次引用 · 2015
7
Dynamically Optimizing Experiment Schedules of a Laboratory Robot System with Simulated Annealing
8 次引用 · 2014
8
Application of robotics to steady state enzyme kinetics: analysis of tight-binding inhibitors of dipeptidyl peptidase IV
7 次引用 · 2003
9
GPCR Assay Automation for Leveraging Lead Optimization
5 次引用 · 2012
10
Intelligent image analysis for error detection and correction in automated laboratory robot systems
4 次引用 · 1998

教职员与研究人员

…

尚未生成