SURGICAL
结直肠癌肝转移中根据KRAS和BRAF状态的手术切缘预后相关性：BRAF-KRAS肝转移协作组
Ferrari C, Molina V, D'Ambrosio GM, Famularo S, Milana F, Patrone R, Russolillo N, Alaimo L, Roldán-Ortiz I, Nocchi N, Wassmer C, De la Serna S, Mocchegiani F, Bitto S, Garancini M, Romano F, Abreu de Carvalho LF, Berrevoet F, Nasto RA, Fallani G
- 发表年份
- 2026
- 期刊
- Annals of surgical oncology
摘要
该论文研究了结直肠癌肝转移患者中，手术切缘状态与KRAS和BRAF基因突变对预后的影响。通过多中心协作分析，发现BRAF突变患者即使切缘阴性预后也较差，而KRAS突变与切缘状态共同影响生存率。
关键词
colorectal liver metastasessurgical marginsKRASBRAFprognosis
相关论文
SURGICAL
📊 2,712 引用
Campbell-Walsh urology
Alan J. Wein editor-in-chief
2012
SURGICAL
📊 2,062 引用
Principles of Robot Motion: Theory, Algorithms, and Implementations
Howie Choset, Jean‐Claude Latombe
2005
SURGICAL
开放获取📊 1,859 引用
Minimally Invasive versus Abdominal Radical Hysterectomy for Cervical Cancer
Pedro T. Ramírez, Michael Frumovitz, René Pareja 等 19 位作者
2018
SURGICAL
📊 1,839 引用
Guideline for Management of the Clinical T1 Renal Mass
Steven C. Campbell, Andrew C. Novick, Arie S. Belldegrun 等 12 位作者
2009