High Throughput Characterization of Polymer Libraries by Diffuse Reflectance Infrared Spectroscopy

摘要

Abstract Diffuse reflectance FTIR (DRIFT) was established as a high throughput characterization method for classic copolymer systems. Four different methyl methacrylate‐based polymer libraries with styrene, N‐ vinylpyrrolidone, 4‐vinylpyridine, or 2‐carboxyethyl acrylate as comonomers were synthesized using an automated/robotic synthesizer platform, and analyzed by 1 H NMR and DRIFT. By multivariate data analysis both data sets were compared and correlations with R 2 between 0.9373 and 0.9971 could be achieved. By this means high throughput screening of comonomer contents of these polymer libraries was enabled.