OTHER
高通量筛选鉴定不依赖mTORC1的TFEB激活剂以促进保护性自噬
Miyano T, Suzuki K, Sera T
- 发表年份
- 2026
- 期刊
- Biochemical and biophysical research communications
摘要
该论文通过高通量筛选方法，发现了不依赖于mTORC1通路的TFEB激活剂，这些激活剂能够促进保护性自噬。研究为神经退行性疾病等自噬相关疾病的治疗提供了新的潜在药物靶点。
关键词
autophagyTFEBmTORC1drug screeningneuroprotection
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